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激光虹膜成形术治疗早期慢性闭角型青光眼观察
时间：2022-11-17 17:28:32 下载该word文档
激光虹膜成形术治疗早期慢性闭角型青光眼观察刘修铎;史春;应坚;徐惠娣;张玮【摘要】AIM:Toevaluatethesafetyofthelaserperipheraliridoplasty(LPIPfortheearly-stagechronicprimaryangle-closureglaucoma(ECPACG.METHODS:Sixty-fiveeyesof36patientswithECPACGreceivedLPIP.Atpreoperativeandpostoperative,patientswereexaminedwithintraocularpressure(IOP,anteriorchamber,opticalcoherencetomography(OCT,visualacuity,visualfield,fundusandcomplications.Themeanfollow-upwas18.2±6.7mo(ranged12~24mo.RESULTS:ThepreoperativeaverageIOPwere23.8±5.6mmHg,postoperative1wk,1,3,6,12moandinthelastfollow-uptimetheaverageIOPwere18.7±3.8,17.9±3.2,17.6±3.5,18.4±3.7,18.6±3.7,and18.6±7.8mmHg.Therewasstatisticaldifferencecomparingwithpreoperative(P<0.05,decreasingaverage6.5±3.1mmHgcomparedwiththepreoperative,thedifferencewasstatisticallysignificant(t=5.32,P<0.05.Postoperative1wk,1,3,6mo,thetrabecular-irisangle(TIA500andtheangleopeningdistanceat500μm(AOD500hadthestatisticaldifferencecomparingwithpreoperative(P<0.05.AtPostoperative1aandthelastfollow-uptime,theTIA500andAOD500didnothavestatisticaldifferencecomparingwithpreoperative(P>0.05.Thepostoperativevisualacuity,visualfield,fundushadnotchanged.Therewerenocomplicationsfound.CONCLUSION:LPIPissafe,andhastheshorttimeeffectinthetreatmentofECPACG.Withelapseoftime,theeffectofLPIPisweakened.Wecan
repeatthetreatment.%目的：观察Nd：YAG532激光虹膜周边成形术(Laserperipheraliridoplasty,LPIP治疗早期慢性闭角型青光眼效果与安全性。方法：2011-09/2012-10内诊断为早期慢性闭角型青光眼患者36例65眼,行LPIP。术前术后观察眼压、前房角、视力、视野、眼底、并发症等情况。随访12~24(平均18.2±6.7mo。结果：术前眼压23.8±5.6mmHg,LPIP术后1wk；术后1,3,6,12mo眼压分别为18.7±3.8,17.9±3.2,17.6±3.5,18.4±3.7,18.6±3.7mmHg,与术前比较差异全部具有统计学意义(P<0.05。最末次随访眼压为18.6±7.8mmHg,与术前比较平均下降6.5±3.1mmHg,差异具有统计学意义(t=5.32,P<0.05。术后1wk；术后1,3,6mo相比术前的前房角角度(TIA500与500μm前房角开放距离(AOD500增大有非常显著差异(P<0.05,术后1a与末次相比术前TIA500与AOD500无统计学意义(P>0.05。术后随访时间内视力无变化,杯盘比无增大,视野损害无进展。结论：激光虹膜周边成形术治疗早期慢性闭角型青光眼安全,短期内有效,中长期效果有回退,可以重复治疗。【期刊名称】《国际眼科杂志》【年(卷,期】2015(000004【总页数】3页(P656-658【关键词】激光;虹膜成形术;青光眼;成像【作者】刘修铎;史春;应坚;徐惠娣;张玮【作者单位】200438中国上海市杨浦区市东医院眼科;200438中国上海市杨浦区市东医院眼科;200438中国上海市杨浦区市东医院眼科;200438中国上海市杨浦区市东医院眼科;200438中国上海市杨浦区市东医院眼科
【正文语种】中文方法:2011-09/2012-10内诊断为早期慢性闭角型青光眼患者36例65眼,行LPIP。术前术后观察眼压、前房角、视力、视野、眼底、并发症等情况。随访12～24（平均18.2±6.7）mo。结果:术前眼压23.8±5.6mmHg,LPIP术后1wk;术后1,3,6,12mo眼压分别为18.7±3.8,17.9±3.2,17.6±3.5,18.4±3.7,18.6±3.7mmHg,与术前比较差异全部具有统计学意义（P＜0.05）。最末次随访眼压为18.6±7.8mmHg,与术前比较平均下降6.5±3.1mmHg,差异具有统计学意义（t=5.32,P＜0.05）。术后1wk;术后1,3,6mo相比术前的前房角角度（TIA500）与500μm前房角开放距离（AOD500）增大有非常显著差异（P＜0.05）,术后1a与末次相比术前TIA500与AOD500无统计学意义（P＞0.05）。术后随访时间内视力无变化,杯盘比无增大,